“Lactate Shift,” Rather Than “Lactate Clearance,” for Serial Blood Lactate Monitoring?

"Lactate Shift," Rather Than "Lactate Clearance," for Serial Blood Lactate Monitoring?

Lactate analyzer with continuous blood sampling for monitoring blood lactate during physical exercise.

To monitor changes in the concentration of blood lactate during physical exercise, we used an automated lactate analyzer based on an electro-enzymatic method with continuous blood sampling through a catheter. The lactate concentration was measured every 2 min; between measurements, the instrument was calibrated with a lactate standard. Ascorbic acid, bilirubin, hemoglobin, creatinine, uric acid...

Lactate revisited : is lactate monitoring beneficial for ICU patients ? REVIEw

Blood lactate levels are frequently measured in critically ill patients. Whilst these measurements are known to be accurate, for the correct interpretation of hyperlactataemia, it is essential to have sufficient understanding of anaerobic and aerobic mechanisms of production and clearance. The consistency of the prognostic value emphasizes the place of lactate measurement in the risk-stratifica...

Prognostic significance of blood lactate and lactate clearance in trauma patients.

BACKGROUND Lactate has been shown to be a prognostic biomarker in trauma. Although lactate clearance has already been proposed as an intermediate endpoint in randomized trials, its precise role in trauma patients remains to be determined. METHODS Blood lactate levels and lactate clearance (LC) were calculated at admission and 2 and 4 h later in trauma patients. The association of initial bloo...

Lactate biosensors for continuous monitoring.

Blood lactate concentration is a highly sensitive measure of tissue oxygen deprivation from ischemia, trauma, and hemorrhage, which can produce life-threatening shock. Significantly, blood lactate is the most reliable end point indicator of resuscitation and predictor of survivability. The need for continuous measurement of blood lactate, and the slowness of discrete conventional photometric as...